SEURAT Biology

For more details, see the Feature List

SEURAT generates a dose response curve using well details

Plot IC50/EC50 Dose Response Curves for Multi Point Assays Biologists can design and deploy SEURAT Forms that include dynamically generated dose response curves based on the multi point assay data stored in their existing database or as loaded into the Synaptic Science native database schema. Points can be dynamically dropped from the interactive dose response chart to see how that effects the prediced curve and users can zoom interactively into areas of interest.

Choose search type and assay name from pre-filled lists	Quick Search Biologists can use the SEURAT Quick Search facility to select their assay from a list of all assays and see every experimental result it has produced. Straight away they have information pertinent to their day-to-day responsibilities without the need to learn a complex interface.
	Advanced Search
	Search by Structure
	Results Display SEURAT returns all results for that assay at the experiment level in the Result Display. The type, units, concentration and concentration units of each assayed lot is shown along with when the assay was performed, comments about the result and information about the notebook and page that contain a record of the experiment.
Results are aggregated to give a row per compound summary. You choose whether to see median, mean, max or min. Mouse over shows per lot results.	Assay Display SEURAT then aggregates the results into a single row per compound in the Assay Display. It is at this point that structural information is shown and at which the user can start to explore the breadth of features offered by the SEURAT discovery platform.

SEURAT intelligently handles experimental complexity by showing imprecise values with their operator and/or standard deviation information while still allowing those columns to be used in sort and mathematical operations. Special symbols (+, ++) are used to notify the user that one or more of the underlying values for a displayed assay result are imprecise (>300 for example).

Biologists can easily add new assays, properties, local structure searches and user defined columns in the Assay Display. They can calculate bins based on ranges in their assays data and color the original column by those bins. They can also look for trends emerging in their assays and study the significance of the statistical spread of an assays data by visualizing assay results via the Tools->Visualize menu option in the Assay Display.

For more details about how to analyze your biological assay results through a step-by-step exploration of your results in the Assay Display see the Features List section of our website or the "Working with the Assay Display" section of the SEURAT Users Guide (this requires you to have contacted us for a username and password).

	Ligand Efficiency Example
	Expanded View